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During bioactivity screening, calicoferol E was found to show inhibitory activity against protein tyrosine phospholipase 1B (PTP1B), with an IC 50 value of 27.28 μM (Yan et al., 2005)

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age, 50 ± 12 years) who were T2D-free at baseline and were submitted to renal transplantation over a 9.6-year median period [interquartile range (IQR): 6.2-10.2 years]