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Animal models have shown that the intact oil has a greater effect on reduction of inflammatory eicosanoids and lipid peroxidation than TQ alone suggesting a synergistic effect for compounds in the whole oil rather than isolated TQ

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Recent datasets refine in-vivo dopamine quinone chemistry, quantify neuromelanin-bound iron catalysis, and stratify idiopathic PD by complex-I deficiency, strengthening that oxidative stress is disease-relevant (not generic) and mechanistically linked to ferroptosis