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Tissue repair and wound healing models — including contraction, granulation tissue formation, angiogenesis, and collagen synthesis in rodent and porcine models Extracellular matrix remodeling — investigation of fibroblast activity, collagen I and III synthesis, elastin production, and glycosaminoglycan deposition in dermal models Copper ion delivery — bioavailable transport of Cu²⁺ as cofactor for lysyl oxidase (ECM cross-linking), superoxide dismutase (antioxidant defense), and cytochrome c oxidase (mitochondrial respiration) Anti-inflammatory signaling — studies examining suppression of NF-κB and associated cytokines (IL-6, IL-1β, TNF-α) in cell and animal models, including an experimental colitis model (Frontiers in Pharmacology, 2025) Aging biology — investigation of the correlation between age-related plasma decline of GHK-Cu and reduction in regenerative capacity
