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Support for fast CBS SNPs includes optimising the pathways above it, using vitamin B12 and choline to encourage homocysteine to be re-methylated

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Proton pump inhibitors (acid blockers) and over-the-counter non-steroidal anti-inflammatory agents can change the environment of the GI tract predisposing to nutrient deficiencies Unfortunately, that isn’t an exhaustive list, but it does give you a pretty good idea of why you should be concerned about your vitamin B12 levels