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Reference Material Used in This Comparison Both compounds are stocked as lyophilised reference material in several vial strengths: Retatrutide – 6mg Retatrutide – 12mg Retatrutide – 24mg Tirzepatide – 5mg Tirzepatide – 10mg Tirzepatide – 30mg What Retatrutide Is Made Of: Structure, Linker and Half-Life Retatrutide is a 39-residue synthetic peptide carrying a C20 fatty diacid attached through a short linker to a lysine in the chain
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All study participants were randomly assigned to an experimental treatment group that received subcutaneous injection of cagrilintide, once-weekly, in doses of either 0.3, 0.6, 1.2, 2.4, or 4.5 mg, as well as a one-daily 3.0 mg dose of liraglutide, and a volume matched placebo for control purposes