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[DOI] [PMC free article] [PubMed] [Google Scholar] 48.Sicard J.F., Le Bihan G., Vogeleer P., Jacques M., Harel J
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These effects of Pycnogenol ® on joints can be explained by previous findings, showing that regular intake of Pycnogenol ® leads to a potent decrease of pro-inflammatory markers like NF-κB and COX-enzymes, as well as a decline in the release of matrix metallopeptidase (MMP) enzymes, that are responsible for destroying cartilage in joints ( In most cases, joint pain is due to damage to the articular cartilage
