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NAC (N-acetylcysteine) and glutathione are not interchangeable—most psychiatric research studied NAC as a glutathione precursor, not direct glutathione supplementation, making supplement claims unproven

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Although OH Py 2 N 2 was designed to serve as a direct antioxidant that functions through radical scavenging and metal-binding, the studies described herein show that the molecule activates multiple biological pathways innate to cells that promote the cells to protect against oxidative stress