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Moreover, the authors showed that IGF-1 stimulates cell proliferation and protein synthesis by activating the phosphatidylinositol 3-kinase (PI3K)/serine/threonine kinase (or protein kinase B, AKT) and extracellular regulated protein kinases (ERK) pathways

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The competitive exercise resulted in noted increases in lipid peroxidation, nitric oxide metabolites, and carbon monoxide, with decreases in reduced glutathione and antioxidant enzyme activity