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Preliminary comparison of real time QPCR with cytogenetic karyotype, hypermetaphase FISH and western blot analysis in CML patients in clinical remission

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Further, basal studies have also shown an attenuated diurnal variation [8, 24] particularly with a loss of the morning peak of ACTH [8, 20, 21, 25, 26] or cortisol [8, 20, 27] while challenge studies often, but not invariably, show a diminished HPA axis responsivity