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Work building on Loren Pickart's foundational research into tripeptide-copper complexes has identified AHK-Cu as a compound of interest specifically for scalp and follicle-targeted activity, citing its structural similarities to and differences from GHK-Cu as potentially relevant to its hair-specific profile

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Patients with Multiple Endocrine Neoplasia syndrome type 2, a genetic condition associated with increased risk of medullary thyroid carcinoma, should also avoid treatment with this medication