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Disclosures: hexin Yan: Nothing to Disclose 2009 COMPARATIVE EVALUATION OF DIAGNOSTIC ULTRASOUND ELASTOGRAPHY WITH GUIDED VIBRATION-CONTROLLED TRANSIENT ELASTOGRAPHY IN PATIENTS WITH CHRONIC LIVER DISEASE Elizabeth Williams 1 Regina Weber 1 Samer Gawrieh 1 Niharika Samala 1 Naga Chalasani 1 Raj Vuppalanchi 1 , 1 Indiana University School of Medicine Background: Non- invasive evaluation of hepatic steatosis and fibrosis is increasingly standard in evaluating and managing patients with chronic liver disease

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Relevant research has shown that lycopene could act on the Nrf2/HO-1 and protein kinase B(Akt)/Nrf2 signaling pathway, induce Nrf2 gene transcription, upregulate the mRNA expression levels of NQO1 and HO-1 , improve the activities of SOD, CAT, and GSH-Px, and reduce the accumulation of ROS and MDA oxidative stress end-products (66–70)

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