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310 In age-related diseases, metformin beneficially enhances mitochondrial function, increases Nrf2 activity, induces autophagy, or ameliorates accelerated aging defects in Hutchinson–Gilford progeria syndrome (HGPS) cells by altering gene splicing through its activation mechanisms

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For everyone else, including general body composition goals, neither peptide has the human evidence base to be recommended over diet, resistance training, or (for weight loss) FDA-approved pharmacotherapy with actual outcome data