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By further comparing the protein expression and cytokine expression in the TAK-242 and TAK-242+ T.cp -MIF groups, it can be preliminarily confirmed that the mechanism of dynamic polarization caused by T.cp -MIF acting on THP-1-derived macrophages may be the binding to TLR4 and then activating the downstream macrophage M1/M2 type polarization-related pathway

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