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Patients receive supplementation with GlyNAC (glycine and cysteine (as N-acetylcysteine)) or placebo for 14-21 days, and limitations in pulmonary function and oxygen saturation improve only in patients supplemented with GlyNAC (but not placebo), but the improvement in pulmonary function and oxygen saturation is higher with advancing age, such that at the end of the supplementation period all patients have similar pulmonary function and oxygen saturation

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Intraoperative ketamine for prevention of postoperative delirium or pain after major surgery in older adults: an international, multicentre, double-blind, randomised clinical trial