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Semaglutide Storage & Handling Storage by format Format Lyophilized (powder, sealed) Storage -4F (-20C) freezer Shelf life Up to 12+ months Format Lyophilized (powder, sealed) Storage 35.6-46.4F (2-8C) refrigerator Shelf life Several months Format Lyophilized (powder, sealed) Storage Room temperature (shipping) Shelf life Stable for several weeks Format Reconstituted (solution) Storage 35.6-46.4F (2-8C) refrigerator Shelf life Use within 28 days Format Reconstituted (solution) Storage -4F (-20C) freezer Shelf life Not recommended - do not freeze Brand pens (Ozempic, Wegovy) follow their own label storage rules