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The dose of ebselen was chosen according to our published study (Figure 3, the protein expressions of GPX1 were significantly increased in peroxynitrite + ebselen group compared with the peroxynitrite-only group, while it was absent in the peroxynitrite + gpx1 –/– group (Figures 3A–C)

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[DOI] [PMC free article] [PubMed] [Google Scholar] 196.Shea D.J., Li Y.W., Stebe K.J., Konstantopoulos K