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Strains like Lactobacillus and Bifidobacterium support the broader microbiome, while Akkermansia is specifically tied to the gut barrier layer

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Clarifying the difference of metabolic profiles and of molecular mechanisms between HFrEF and HFpEF might provide clinical significance of carnitine metabolism as new therapeutic target for metabolic disorder in hypertensive HFpEF, remaining unmet medical needs in cardiovascular medicine