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βTesofensine produced weight loss significantly greater than placebo and was more effective than any currently approved obesity drug at the time.β β Astrup et al., The Lancet Additional Findings: β The majority of weight loss came from visceral fat and abdominal adiposity β Lean body mass was preserved , unlike with most appetite suppressants β Participants reported reduced hunger and better diet adherence β Tesofensine significantly improved waist circumference , lipid profiles, and fasting glucose These findings have led to continued interest in Tesofensineβs use for body recomposition β not just for general weight loss, but for fat-specific reduction without muscle sacrifice
DRB00602
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Glutathione S-transferase T1 (GSTT1) null polymorphism, smoking, and their interaction in coronary heart disease: a comprehensive meta-analysis
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