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The use of fluorescence resonance energy transfer-based biosensors of various GPCRs indicated the formation of distinct ligand-specific receptor conformations (Kim et al., 2022), and recent technical advances have revealed a far wider and more dynamic range of receptor and β -Arr conformations that are ligand and receptor specific (Lee et al., 2016
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Erdile LF, Brandt MA, Warakomski DJ, Westrack GJ, Sadziene A, Barbour AG, Mays JP
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