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Additionally, oxidative stress leading to neuronal and glial cell dysfunction and cell death induced by caspases, mitogen-activated protein kinases and protein kinase C may contribute to development of oxaliplatin-induced CIPN (Carozzi et al., 2015)

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In this comprehensive article we review seminal work that led to the discovery and description of the pathway that date back now for 80 years, and address recent results about genetic and metabolic mechanisms that regulate its activity

Glutathione is a unique form of Reduced L