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We then extracted particles that were at the two ends of this variability component for further local refinement (Extended Data Fig
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12 Dynamic changes and interactions of immune cells in the joint region of OA 12.1 Dynamic changes among immune cells in the OA joint During the progression of osteoarthritis (OA), the dynamic changes in immune cells are a critical feature of disease development, spanning from the early inflammatory phase to the late cartilage destruction phase
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