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In search of a pan-coronavirus vaccine: next-generation vaccine design and immune mechanisms | Cellular & Molecular Immunology
This approach has allowed us to identify novel DNA adducts, including cross-links in several experimental settings, including tobacco-specific nitrosamine NNK 71 , the gut bacterial-derived genotoxin colibactin 72 , and the chemotherapy agents busulfan and cyclophosphamide 73,74
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Ferulic acid-chitosan nanoparticles (FA-ChNPs) act as a multimodal radiosensitizer through three synergistic mechanisms: enhancing radiation-induced DNA damage by suppressing cytokine-mediated survival signaling and reprogramming the tumor immune microenvironment through dual cytokine modulation-downregulating radioresistance-associated cytokines while upregulating radiosensitizing cytokines 20,21,22