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The symptoms are reminiscent of bi-polar episodes but far less sharp – weepy and sensations of grief, irritability, disinterest, and brain either racing or foggy, bruxism, tension, and outbreaks of irrational anger

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NMN was administered via gavage at a dose of 1 mg/g of body weight either at the same time for 21 days or after colitis induction with dextran sodium sulfate for the last 14 days