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This alteration of its functions together with astrocyte-mediated remodeling of the extracellular matrix and profibrotic processes amplify the biomechanical and vascular stress associated with glaucoma occurring in the optic nerve head (Roberts et al., 2010

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However, the mice that were fed the BPA rich diet together with the methyl rich diet, did not show the phenotypic expression of the Agouti gene as these mice were small, not overweight, with brown fur