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National institutes of health consensus development project on criteria for clinical trials in chronic graft-versus-Host disease: I

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In two randomized, placebo-controlled, double-blind ascending-dose trials in healthy adults (aged 21–61), a single subcutaneous injection of CJC-1295 with DAC produced dose-dependent increases in mean GH of roughly 2- to 10-fold for six days or more, and increases in IGF-1 of about 1.5- to 3-fold for nine to eleven days