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For example, structural and computational analyses of the Leishmania surface metalloprotease GP63 have identified conserved extracellular domains suitable for antibody targeting, while docking and MD simulations have characterized accessibility and stability within parasite-specific proteolytic niches, illustrating how structural mapping can directly inform epitope selection and activation logic in ID-ADC development (Ali et al., 2025)
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Try to avoid pairing it with high-calcium foods, since calcium may reduce absorption†