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Keywords: surfactant-based drug delivery, breast cancer, polymeric micelles, nanoemulsions, multidrug resistance (MDR), targeted therapy, self-emulsifying drug delivery systems (SEDDSs), clinical nanomedicine, stimuli-responsive nanocarriers 1

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Dietary supplementation or restriction of amino acids in worms, flies and mice modulates lifespan and health, which has been associated with changes in mitochondrial biogenesis, antioxidant response, as well as the activity of tricarboxylic acid cycle and respiratory chain