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3.1.2 ARPE-19 cell model The ARPE-19 cell line is derived from adult retinal pigment epithelial (RPE) explants, and ARPE-19 cells can be extensively expanded, providing a relatively stable source of retinal epithelial cells for functional and genetic research ( 2 for 4 h, the barrier function was impaired (Table 1)

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Materials and methods Chemicals The reference phenolic compounds used in this study (Table 1) as well as galantamine (reference drug) and scopolamine hydrobromide (S1875-5G) were acquired from Sigma-Aldrich (St