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CJC-1295 Without DAC addresses these stability vulnerabilities through four targeted amino acid substitutions that were identified through systematic structure-activity relationship research examining which positions in the GHRH(1-29) sequence were most vulnerable to enzymatic inactivation and most tolerant of modification without loss of GHRH receptor affinity

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[DOI] [PubMed] [Google Scholar] Svensson S, Strömberg P, Sandalova T, Höög J