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It has, however, been found that tumor cell ferroptosis is promoted by 15-lipoxygenase-catalyzed lipid peroxidation in cellular membranes [32]

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Le facteur de transcription Nrf2 régule l'expression des gènes codant pour les enzymes de synthèse du glutathion, notamment la glutamate-cystéine ligase (GCL), l'enzyme limitante