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The mechanism of action involves disruption of bacterial cell membrane integrity and interference with essential enzymatic processes
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Patients with MS are 20 times more likely to develop TN, which affects 2%–5% of patients.21 In 3.6% of cases, secondary TN is caused by a bone disease of the skull (osteomyelitis, Paget disease, osteoma), arteriovenous malformation, dural fistula, pontine infarction, tuberculoma, cholesteatoma, arachnoiditis, hydrocephalus, lipoma, syphilis, diabetes mellitus, malaria, etc.19 Trigeminal neuralgia with concomitant continuous pain The ICHD-3 recognises that, in addition to the characteristic paroxysms, patients with classical or idiopathic forms of TN may present continuous or near-continuous pain between attacks