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Yet, mutations in the remaining genes, although rare in frequency, have been unequivocally established as PD-causative and account for the majority of autosomal dominant ( SNCA , LRRK2 , HTRA2 , and VPS35 ) or recessive PD cases ( PRKN , PINK1 , DJ-1, ATP13A2, PLA2G6, FBXO7, DNAJC6 , and VPS13C )
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