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Overexpression of Wnt inhibitory factor 1 (WIF1) suppresses the Wnt/β-catenin signaling pathway, reduces the activity of the AMPK/mTOR signaling pathway, and improves the mitochondrial function caused by diabetic retinopathy

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Among the transgenic cohorts, those treated intranasally with GHK-Cu exhibited improved cognitive performance and fewer, smaller, and less densely stained plaques compared to intranasal saline-treated cohorts